Tag Archives: serotonin

I know What You Should Do This Summer!

In this blog post: July’s PubSci; Listen to the Number 1 Science Podcast, and what to do this summer

First of all, huge thanks to Caroline Copeland from King’s College London for June’s PubSci when she talked about the problems with how government drugs policy is made in England and Wales (compared to what the science tells us) in The Drugs [laws] Don’t Work. Once again the room was packed and even with a really engaged Q&A session, we managed to get the room turned around in time for England’s first World Cup match (against Croatia) at 9pm, which our hosts at The Old King’s Head really appreciated.

A talk in a pub room with an England flag and another picture of football on TV
Courtesy of Andy Powell

July’s PubSci is booking fast

As mentioned in my previous blog post, on Wednesday 22nd July, PubSci is delighted to welcome Dr Parry Hashemi from Imperial College London to talk about the “happiness molecule” in The Sound of Serotonin – Listening to Brain Cells.

Visualisation of a synapse with serotonin crossing between brain cells. The synapse looks like two flat-faced tadpoles kissing

Serotonin’s relationship with depression is complex, and assessing neurotransmitter levels in living brains remained a challenge for years. Now Dr Hashemi’s team has developed a revolutionary, non-invasive technique for tracking serotonin levels in real time and even turning the results into music.

With 2/3 of tickets already snapped up at the time of writing, this could be one of our most popular talks ever. Don’t miss the chance to reserve a place — head over to the Eventbrite booking page ASAP, where you’ll find full details, ticket info, and a link to reserve your spot.

The venue is PubSci’s regular home, The Old King’s Head near Borough Market, which offers a great range of drinks, has a happy hour before 7pm, and opens the kitchen serving classic pub grub especially for us. Doors open at 6.30 for a 7pm start. Talks generally run for ~45 minutes and are followed by a Q&A session. Full address on the booking page.

As most of you know by now, PubSci talks are pay-what-you-can: You can make a contribution when booking on Eventbrite. We have no other source of funding. There are two ticket options:

Book for one + Support PubSci (max 1 ticket) if you prefer to contribute when booking – this option also reserves you one spot at the event. You may need to scroll down to see this option on Eventbrite.

Book without donating (max 4 tickets) if you prefer to put cash in the pot on the night.

Yellow smiley face

I used this Smiley for last month’s talk on recreational drugs and government policy and it seems appropriate for a talk on serotonin too!

Of Levitating Hamsters and Other Animals

Why so many cats in science

Many thanks to those of you who helped to pack out my humorous-but-fact-filled science talk at London Fortean Society on the final day of June.

The Levitating Hamster and the Salmon of Doubt went down a storm, it seems – I certainly had a great time, even if the levitation demo didn’t go quite as well as in rehearsal – and somebody picked up a pub quiz-winning animal fact that came in handy the following day at April PubSci speaker, Joanna Bagniewska’s Pint of Knowledge talk about animal butts!

No PubSci in August (but there is an eclipse)

It’s official, there’s no PubSci in August. I’m giving myself a little holiday and going to sSpain to see the total eclipse of the sun on 12th August. The path of totality won’t pass over the UK. It begins in northern Russia, loops round the Arctic circle to pass through Greenland and the west coast of Iceland before touching land again at the northwest corner of Spain where it passes diagonally to the south west and over the Balearic islands before finishing in the Mediterranean sea.

The tip of Cornwall will see around 96% totality (96% of the sun covered by the new moon) but even the remaining 4% of the sun – if visible in a cloudless sky – will remain intensely bright and must not be looked at directly except with special eclipse viewing specs. It’ll be interesting but it won’t be an eclipse. To experience an eclipse, over 99.5% coverage is required. I wrote about some of the experiences of seeing an eclipse in my 2024 blog piece after the four minute long Mexican eclipse.

Those lovely folk at Royal Museums Greenwich (AKA Greenwich Observatory) have put together an eclipse guide for anybody wondering what to expect from a partial eclipse of the sun. Talking of eclipses, perhaps nobody did more to bring them to public consciousness than the late, great, laryngitic Welsh singer Bonnie Tyler who sadly died yesterday. Feel free to indulge in her 5 1/2 minute, Meat Loaf-inspired peak ’80s power ballad (no, I don’t understand the video either, nor do I want to).

Anyhoo…talking of actual eclipses, George Holdaway and I take a deep dive into the science, culture, and history of total eclipses of the sun in…

The Number 1 Science Podcast

The Science Show is a magazine-style miscellany packed with news, interviews, chat and discussions, plus great music and cultural crossovers. This month’s show discusses recent findings about dark energy, looks at the weirdest sourdough ever baked, dives into eclipses and shares some of the best science-related things to do in London this summer, including art and theatre.

I’m particularly chuffed that, within a day of launching Episode 9 of The Science Show, it hit the top spot in MIxcloud’s science chart and zoomed into the Top 20 of the overall Podcast and Talk charts!

And that’s not even the best bit… Our show is currently rated above four top notch, highly professional, and long-established podcasts — including Neil deGrasse Tyson. I knoooow. Consider my mind well and truly blown.

Science Show #9 is ranked above Neil deGrasse Tyson

We’d love you to give it a listen and push it even further up the podcast charts before Tuesday when they reset.

I know What You Should Do This Summer

So there’s no PubSci in August, both Wimbledon and the footy and will be finished, and the eclipse is only 2 minutes long at best, so how are you going to spend your free time in London? Fear not, The Science Show podcast is here! I won’t give you the hard sell again, but it really is packed with science news and some brilliant science-related events happening from late July through to September, including a highly creative musical about Laika the first dog in space and some major exhibitions with scientific content.

However, there were a couple of things we couldn’t fit in, so I’ll share those with you here:

A friend recently decided to start his quest for astrobiology by visiting the London Wetlands Centre to go birdwatching, on the basis that he needs to train his eyes and brain to recognise unfamiliar life forms on Earth before turning his attention towards space. I don’t know if that’s how everybody gets into astrobiology, but on Friday 24th July, Astronomer Royal, Michele Dougherty, looks at the icy moons of Jupiter and Saturn and asks whether Ganymede, Callisto or Europa could host life entirely separate from what we find on Earth. Information and booking here.

On Friday 31st July at 6.30 pm join author and astrophotographer Josh Dury for an evening talk exploring the importance of preserving dark skies , hosted by the astronomers of the Royal Observatory Greenwich in the National Maritime Museum. 

Copies of Josh’s book, 52 Assignments: Night Photography, will be on sale on the night and available as an optional addition to the event ticket. Tickets are just £10 (students £9), available here.

Centre of the Cell at Queen Mary University, London (Whitechapel) has lots of family-friendly events in July and August. Learn about your body’s largest organ in Skin Deep, step into the past, present, and future of cell biology in CELLebration, or build a brain to understand how AI works in Artificial Intelligence – but where is the intelligence?

Mostly aimed at children aged 7-11 and their adults, tickets start at £7.50 details of all events can be found at https://www.centreofthecell.org/whats-on/events/

And talking of activities to keep any young people in your life busy over the summer, lots of institutions and museum have a programme of activities during the school holidays and you could do worse than checking out the Royal Institution’s summer workshop programme (where you might even bump into me).

PubSci event programme

PubSci’s Spring / Summer Programme will soon be replaced by Summer / Autumn covering September to the end of the year. I’m already excited about the programme and can’t wait to share it with you. For now, here’s the current one.

Well that’s it from me. Hope to see you at the Old King’s Head on 22nd July for The Sound of Serotonin – Listening to Brain Cells with Dr Parry Hashemi.

Richard (Science communicator and PubSci organiser/host)

10th July 2026

Mid June Blog: July PubSci is back on! Plus June hot press info, a new Events Programme, and amazing things to do.

TONIGHT (17th June)

If you’re coming to The Old King’s Head for tonight’s PubSci, here’s an important update:

  1. It’s warm today – which means it’s gonna be even warmer in the upstairs room.
    • We have to keep windows closed due to noise from outside, so wear light clothes and bring a small fan
      • We’ll ventilate before the talk and during the break so if you sit by a window please leave it open until the the event starts.
  2. It’s football today, so the pub will be busy and noisy downstairs.
    • Please be patient with the staff, know what you’re ordering and remember that you can order at the foot of the stairs, but please wait at the open door and don’t enter the bar area.
      • If you’re eating, order early (there are menus and a Specials board upstairs) and listen out for your name / order.
  3. It’s not just any football, it’s England’s first game of the men’s World Cup
    • Greg, the landlord, told me he could have filled the pub three-times over with football bookings, and it’s a sign of PubSci’s long relationship with the Old King’s Head that he’s honouring our event booking tonight.
      • Please be super-lovely to the staff, and spend loads at the bar!
  4. The match kicks off at 9pm, when PubSci usually wraps up and it could get noisy from 8.30
    • We’ll pack up the screen and projector during the break, and finish the Q&A no later than 8.45
      • Please keep questions clear and brief, without long statements or pronouncements
  5. We’ll be handing the room back to anybody who wants to watch upstairs
    • For once, there won’t be lots of time for socialising after the event
    • As soon as we finish, we need to quickly turn the room around (possibly literally) and open the doors
      • Please help by returning your glasses to the downstairs bar and your plates to the upstairs bar.
      • If we need to move chairs, please help us with that too so we can keep musing the pub
  6. Don’t be put off
    • The side door will be open, so you won’t need to struggle through a sea of footy fans when arriving or leaving
Somebody shaking round, white pills out of a bottle

July’s PubSci is back on!

We postponed Marcus du Sautoy’s planned July talk as it clashed with the first semi-final of the World Cup. However, I have arranged a different talk for the following week when the football is all over.

Yellow smiley face

On Wednesday 22nd July, Dr Parry Hashemi from Imperial College will talk on The Sound of Serotonin –
Listening to Brain Cells
. [Update, 7/7/26: Booking is open on eventbrite and half the tickets have already gone!]

Serotonin is popularly known as the happiness molecule but its relationship with depression is complex, and measuring neurotransmitters in living brains remained a challenge for years.

Now Dr Hashemi’s team at Imperial College has developed a revolutionary, non-invasive technique for diagnostically tracking serotonin levels in real time and turning the results into music.

Tickets are available on Eventbrite.

30th June 2026: Of Doubtful salmon and Hovering Hamsters

Can hamsters levitate? Do salmon emote? Did herring inspire a Doctor Who spoof? Science communicator and host of PubSci, Richard brings some of the quirkiest stories of animals in science to the London Fortean Society in a not-to-be missed event on Tuesday 30th June: The Levitating Hamster and the Salmon of Doubt.

A hamster riding on a doubtful-looking salmon

This is not a PubSci event, so you’ll need to book through London Fortean Society at https://wegottickets.com/f/21077. Their venue is The Bell on Middlesex Street, London E1 7EX (Liverpool Street / Aldgate East).

There’s a new event programme

The PubSci Spring / Summer Programme has finally been uploaded. You’ll notice it doesn’t go very far into the future – that’s because the world cup and August’s total solar eclipse have changed a few plans – but it’s still worth looking at and printing out.

A radio show to delight your ears

Episode #8 of The Science Show was broadcast on Monday 1st June and is available to stream now as a podcast. In this show:

• George Holdaway joins me to discuss the latest science news including: How fungi can trigger ice and rain; the perilous state of Antarctic ice; NASA’s moon base plans; Pluto and Plutino; and String Theory emerging from nowhere

• George and I take a Random Walk from Mercury to Murder via Evangelista Torricelli, Toxic Hats, and Tycho Brahe.

Dr Parry Hashemi from Imperial College London talks neurotransmitters, brain organoids, and turning serotonin into music.

• Plus details of the best science-related events in London and beyond – including this weekend’s Great Exhibition Road Festival where Dr Hashemi’s team has an amazing interactive installation that allows you to listen to happiness in the brain! – and, as always on the truly unique Science Show, we throw in some excellent music for good measure.

Stream it here https://tinyurl.com/TheScienceShow-Episode-8

And I’m delighted to say that, within days up release, Show 8 shot to the top of the Science charts and reached number 23 among all podcasts on Mixcloud! A huge Thank You to those who listen in live or stream the podcast. If you haven’t yet, you can find out what you’ve been missing at https://www.mixcloud.com/The_Science_Show/

Anyhoo, I’ll be back with an update soon. Meanwhile, I hope to see you all tonight.

Richard (Science communicator and PubSci organiser/host)

17th June 2026

Designer Drugs 101: a Review

Many people say that the UK has some very strange, outdated laws – citing anecdotal examples involving Welshmen in Chester after sun-down. I don’t think you need to go much farther than our drugs legislation to find really loony stuff:

Last night I attended a talk by Dr James Moffat of St. George’s University on the subject of Pharmacology. Dr Moffat opened by stating that he is a cardiovascular specialist and that there will definitely be some questions raised by his talk that require a neurobiologist, or a lawyer, or a politician to give us the sort of detail we are looking for.

He started off by showing us a line of powder on a mirror and asking us to identify it. Naturally the consensus was Cocaine but the photograph was of Salbutamol (commonly known as “Ventolin”) which saves more lives than Cocaine will ever take.

He explained that the brain works by pattern recognition and that it determines what it has taken by which receptors the chemical has triggered. He demonstrated this by asking us to imagine that our brains were simplified and had 1 receptor for each celebrity. Our eyes receive parts of these celebrities and our ‘celebrity receptors’ tell us who they have seen. We were shown a slide of George Clooney’s mouth, and another with Angelina Jolie’s eyes. In both cases the audience as a unit managed to identify the celebrities. Dr. Moffat then unveiled his scariest slide of all: an amalgam of Clooney and Jolie (“Georelina Cloolie”?). He explained that the brain receives the effects of chemicals in the same way: if a drug is designed to affect two receptors, we’ll recognise both at once with different parts of our brain.

Designer drugs target receptors in the brain responsible for releasing neurotransmitters, the key compounds targeted are: serotonin, which induces the happy response; dopamine, responsible for the reward response and addictive qualities; and noradrenalin, the effects of which are complex and still being discovered. The experience you get from taking the substance is based on the extent to which the substance interferes with normal brain activity in the receptors.

Substances such as caffeine, nicotine, and alcohol also interfere with the natural function of the brain in very similar ways. Why are they legal and other drugs aren’t? Also, what about ‘legal highs’ purchased in new age shops? These aren’t FDA approved drugs that get criminalised when new evidence comes to light: these have never been through any kind of official regulatory body whatsoever, nor do they need to have undergone any testing whatsoever. As Dr. Moffat puts it: “‘legal highs’ are an experiment on the general public done by scumbags”.

Let me stop for a moment and point something out here: an English establishment can be shut down for continuing to sell food where the ingredients are listed only in a foreign language because there is a good chance the consumer won’t know what they are consuming, and yet there is little to no regulations on the sale of substances for which the molecular structure is completely unknown. Something is very clearly wrong here.

The criminalisation of substances can, in some cases (such as in Phenethylamines), lead to the outlawing wholesale of any substance which contains the same molecular structure as the banned substance (except where it already has proven medicinal benefits, such as Bupropion). We are at a point now where we ban imaginary drugs and make life difficult for medical researchers without actually hindering the manufacturers of ‘legal highs’ – all they need to do is change a single atom in the molecule and the substance is unknown again. The legislation does not work as intended for anyone.

The questions section was the longest I had ever witnessed in a PubSci event. Even so, I came away from this talk with more questions:

  • How can we get accurate data on the harmful effects of narcotics in isolation? In the real world we don’t get someone admitted with just one thing in their system and to do so as a controlled experiment would be completely unethical.
  • Can we justify banning anything when alcohol abuse is filling our A&E wards on a regular weekly basis? On the one hand it feels a little bit like removing the brakes because road accidents are inevitable; On the other hand, I know of at least one case where a person refused medical attention for a copiously bleeding injury because he didn’t want to be ‘outed’ with substances in his system.
  • Does more money need to be spent on neurological research to remove the faulty parts of our brain that choose the reward response regardless of the cost to ourselves and others? I ask this as an unrepentant caffeine addict who is strongly opposed to drugs and tobacco. I fear the law may need to be made by more logical brains than we can offer it.
  • Who do I talk to about criminalising George Clooney’s eyes?

I don’t know who can answer these questions. Maybe you can help.

The PubSci organisers would like to thank Palaeosam for writing this review – check out his blog for other reviews and interesting stuff!